Professor at Uniformed Services University of the Health Sciences, Bethesda, MD USA, United States
Short Biography 🎓📚
Dr. Pushpa Sharma is a distinguished researcher and professor specializing in trauma and critical care research. With a strong academic foundation in public health sciences and international research training, she has dedicated her career to understanding metabolic and inflammatory responses in hemorrhagic shock and traumatic brain injuries. Her pioneering work on sodium pyruvate and B-hydroxybutyrate resuscitation has provided valuable insights into extending the “golden hour” for trauma patients. Dr. Sharma continues to lead innovative studies aimed at improving survival and recovery in critical care settings.
Professional Profile
Educational Background 🎓💼
Dr. Pushpa Sharma earned her Ph.D. in Public Health Sciences from the All India Institute of Medical Sciences (AIIMS), New Delhi, India. She was awarded prestigious international research fellowships, including the Commonwealth Foundation Fellowship at the Royal Postgraduate Medical School, London, England; a fellowship at the Karolinska Medical Institute, Sweden; and an NSERC Fellowship in Neurosciences at the University of Western Ontario, Canada.
Professional Experience 🚀📖
Dr. Sharma is a Professor at the Uniformed Services University of the Health Sciences (USUHS), Bethesda, Maryland, USA, in the Department of Anesthesiology. She has been actively engaged in translational and experimental research focused on trauma, hemorrhagic shock, and metabolic resuscitation strategies. Her extensive research has been supported by federal agencies such as USUHS and ONR, with projects investigating the role of metabolic antioxidants, energy metabolites, and complement activation in hemorrhagic shock and polytrauma models. Over the years, she has contributed significantly to the advancement of critical care and trauma medicine.
Research Interests🔬📊
Dr. Sharma’s research interests encompass blood-based biomarkers of mitochondrial damage following traumatic brain injury (TBI) and polytrauma in both animal models and human subjects. She explores metabolic interventions to enhance resuscitation strategies and improve survival rates following hemorrhagic shock. Her work focuses on understanding the mechanisms of energy metabolism, inflammation, and immune response in trauma patients.
Publications
- “Cancer and COVID-19: Unravelling the Immunological Interplay with a Review of Promising Therapies Against Severe SARS-CoV-2 for Cancer Patients”
- Journal: Journal of Hematology and Oncology
- Year: 2023
- DOI: 10.1186/s13045-023-01432-6
- “A Novel Therapeutic Approach with Sodium Pyruvate on Vital Signs, Acid–Base, and Metabolic Disturbances in Rats with a Combined Blast and Hemorrhagic Shock”
- Journal: Frontiers in Neurology
- Year: 2022
- DOI: 10.3389/fneur.2022.938076
- “Animal Models of Traumatic Brain Injury: A Review of Pathophysiology to Biomarkers and Treatments”
- Journal: Experimental Brain Research
- Year: 2021
- DOI: 10.1007/s00221-021-06178-6
- “Effects of Pyruvate Administration on Mitochondrial Enzymes, Neurological Behaviors, and Neurodegeneration After Traumatic Brain Injury”
- Journal: Aging and Disease
- Year: 2021
- DOI: 10.14336/AD.2020.1015
- “Colchicine, Aspirin, and Montelukast—A Case of Successful Combined Pharmacotherapy for Adult Multisystem Inflammatory Syndrome in COVID-19”
- Journal: Journal of Global Infectious Diseases
- Year: 2020
- DOI: 10.4103/jgid.jgid_296_20