Ass. Prof. at Wrocław Medical University | Poland
Assoc. Prof. Dr. Kamila Dus-Szachniewicz has an extensive background in clinical and experimental pathology, with a strong focus on Experimental Methods in cancer research. Her career reflects a deep integration of Experimental Methods in proteomics, tumor microenvironment modeling, and innovative diagnostic approaches. She works at Wrocław Medical University, advancing Experimental Methods that combine optical tweezers technology and mass spectrometry for precision oncology. Her leadership in pioneering Experimental Methods has resulted in several patents and influential publications. This summary highlights her capacity to merge fundamental science with practical applications, pushing the boundaries of Experimental Methods in medical diagnostics, cancer cell interaction analysis, and therapeutic development within translational oncology.
Professional Profiles
Google Scholar Profile | ORCID Profile
Education
Assoc. Prof. Dr. Kamila Dus-Szachniewicz has pursued academic excellence through a comprehensive education grounded in Experimental Methods and biological sciences. She earned her master’s in biology, specializing in genetics and microbiology, further shaping her foundational understanding of cellular systems. Her Ph.D. in Medical Sciences integrated Experimental Methods to analyze colorectal adenoma and carcinoma through proteomics. Later, she completed her Doctor of Medical Sciences (habilitation), employing Experimental Methods such as optical tweezers to assess lymphomas under diverse microenvironmental conditions. This educational journey reflects a consistent emphasis on Experimental Methods, providing the skills and theoretical grounding essential for innovation in modern cancer research and diagnostic tool development.
Experience
Assoc. Prof. Dr. Kamila Dus-Szachniewicz’s professional experience is distinguished by her consistent application of Experimental Methods across multiple high-impact research areas. At Wrocław Medical University, she developed proteomic techniques for FFPE tissue analysis, enhancing cancer biomarker discovery through advanced Experimental Methods. She established and characterized three-dimensional lymphoma spheroid models, integrating Experimental Methods to simulate tumor microenvironments and improve translational relevance. Moreover, she applied optical tweezers-based Experimental Methods to study cell adhesion, develop hybrid spheroids, and support personalized oncology. Her role as a research project leader demonstrates her ability to design, implement, and manage sophisticated Experimental Methods to address pressing challenges in hematological malignancy diagnostics and therapeutic strategy development.
Research Interest
Assoc. Prof. Dr. Kamila Dus-Szachniewicz’s research interests are deeply rooted in the innovative use of Experimental Methods to solve complex problems in oncology. She focuses on proteomic profiling of cancer progression, enabling precision diagnostics through optimized Experimental Methods. Her work includes constructing advanced tumor models to mimic lymphoma-microenvironment crosstalk, improving Experimental Methods for studying drug response and cell-cell interaction. Additionally, she explores the use of optical tweezers-based Experimental Methods to analyze mechanical and adhesive properties of cancer cells, linking physical forces with therapeutic outcomes. These research interests collectively illustrate her commitment to advancing Experimental Methods for more predictive, precise, and clinically relevant cancer research approaches.
Award and Honor
Assoc. Prof. Dr. Kamila Dus-Szachniewicz has been recognized for her outstanding contributions to science through several prestigious awards and honors emphasizing Experimental Methods in oncology. Her pioneering use of optical tweezers as part of Experimental Methods in hematological cancer research garnered institutional and national funding. The successful completion of competitive projects has elevated Experimental Methods as transformative tools in diagnostic innovation. Her contributions have also been acknowledged through grants promoting translational applications of Experimental Methods in cancer biology. These honors underscore her leadership and vision, reaffirming the importance of Experimental Methods in redefining how cellular interactions and therapeutic targets are identified and validated in modern medicine.
Research Skill
Assoc. Prof. Dr. Kamila Dus-Szachniewicz has developed a powerful set of research skills, all interconnected by her mastery of Experimental Methods. She has refined skills in proteomic analysis using mass spectrometry, a cornerstone of modern Experimental Methods for biomarker discovery. Her ability to design and manage complex cell culture systems, including hybrid lymphoma spheroids, highlights her proficiency in Experimental Methods modeling disease biology. Furthermore, her technical expertise in optical tweezers-based assays exemplifies how Experimental Methods can quantify mechanical properties of cancer cells. Collectively, her research skills demonstrate a profound capacity to implement and advance Experimental Methods that bridge molecular insights, cellular behavior, and therapeutic innovation in oncology.
Publication Top Notes
Title: Extensive quantitative remodeling of the proteome between normal colon tissue and adenocarcinoma
Journal: Molecular Systems Biology
Authors: JR Wiśniewski, P Ostasiewicz, K Duś, DF Zielińska, F Gnad, M Mann
Citation: 274
Title: Proteomic workflow for analysis of archival formalin‐fixed and paraffin‐embedded clinical samples to a depth of 10 000 proteins
Journal: PROTEOMICS–Clinical Applications
Authors: JR Wiśniewski, K Duś, M Mann
Citation: 174
Title: Absolute proteome analysis of colorectal mucosa, adenoma, and cancer reveals drastic changes in fatty acid metabolism and plasma membrane transporters
Journal: Journal of Proteome Research
Authors: JR Wiśniewski, K Duś-Szachniewicz, P Ostasiewicz, P Ziółkowski, ...
Citation: 89
Title: Toward controlled photothermal treatment of single cell: optically induced heating and remote temperature monitoring in vitro through double wavelength optical tweezers
Journal: ACS Photonics
Authors: S Drobczyński, K Prorok, K Tamarov, K Duś-Szachniewicz, VP Lehto, ...
Citation: 43
Title: Physiological hypoxia (physioxia) impairs the early adhesion of single lymphoma cell to marrow stromal cell and extracellular matrix. Optical tweezers study
Journal: International Journal of Molecular Sciences
Authors: K Duś-Szachniewicz, S Drobczyński, P Ziółkowski, P Kołodziej, ...
Citation: 28
Title: Pattern of melanotransferrin expression in human colorectal tissues: an immunohistochemical study on potential clinical application
Journal: Anticancer Research
Authors: K Duś-Szachniewicz, P Ostasiewicz, M Woźniak, P Kołodziej, ...
Citation: 24
Title: Real-time force measurement in double wavelength optical tweezers
Journal: Journal of the Optical Society of America B
Authors: S Drobczyński, K Duś-szachniewicz
Citation: 19
Title: Quantitative analysis of gene expression in fixed colorectal carcinoma samples as a method for biomarker validation
Journal: Molecular Medicine Reports
Authors: B Ostasiewicz, P Ostasiewicz, K Duś-Szachniewicz, K Ostasiewicz, ...
Citation: 18
Title: Protein tyrosine phosphatase receptor R and Z1 expression as independent prognostic indicators in oral squamous cell carcinoma
Journal: Head & Neck
Authors: K Duś‐Szachniewicz, M Woźniak, K Nelke, E Gamian, H Gerber, ...
Citation: 18
Title: Insulin-like growth factor-2 is induced following 5-aminolevulinic acid-mediated photodynamic therapy in SW620 human colon cancer cell line
Journal: International Journal of Molecular Sciences
Authors: M Woźniak, K Duś-Szachniewicz, P Ziółkowski
Citation: 18
Title: Development and characterization of 3D hybrid spheroids for the investigation of the crosstalk between B-cell non-Hodgkin lymphomas and mesenchymal stromal cells
Journal: OncoTargets and Therapy
Authors: K Duś-Szachniewicz, K Gdesz-Birula, G Rymkiewicz
Citation: 16
Title: Proteomic-based analysis of hypoxia-and physioxia-responsive proteins and pathways in diffuse large B-cell lymphoma
Journal: Cells
Authors: K Duś-Szachniewicz, K Gdesz-Birula, K Zduniak, JR Wiśniewski
Citation: 15
Title: The assessment of the combined treatment of 5-ALA mediated photodynamic therapy and thalidomide on 4T1 breast carcinoma and 2H11 endothelial cell line
Journal: Molecules
Authors: K Zduniak, K Gdesz-Birula, M Woźniak, K Duś-Szachniewicz, ...
Citation: 14
Title: Immunohistochemical study of nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 in invasive breast carcinoma of no special type
Journal: Experimental and Therapeutic Medicine
Authors: K Symonowicz, K Duś-Szachniewicz, M Woźniak, M Murawski, ...
Citation: 14
Title: Differentiation of single lymphoma primary cells and normal B-cells based on their adhesion to mesenchymal stromal cells in optical tweezers
Journal: Scientific Reports
Authors: K Duś-Szachniewicz, S Drobczyński, M Woźniak, K Zduniak, ...
Citation: 13
Title: Vacata‐and divacataporphyrin: New photosensitizers for application in photodynamic therapy—an in vitro study
Journal: Lasers in Surgery and Medicine
Authors: M Klyta, P Ostasiewicz, K Jurczyszyn, K Duś, L Latos‐Grażyński, ...
Citation: 13
Title: Spectral analysis by a video camera in a holographic optical tweezers setup
Journal: Optica Applicata
Authors: S Drobczynski, K Dus-Szachniewicz, K Symonowicz, D Glogocka
Citation: 10
Title: Formation of lymphoma hybrid spheroids and drug testing in real time with the use of fluorescence optical tweezers
Journal: Cells
Authors: K Duś-Szachniewicz, K Gdesz-Birula, E Nowosielska, P Ziółkowski, ...
Citation: 9
Title: Immunocytochemical studies on the nuclear ubiquitous casein and cyclin-dependent kinases substrate following 5-aminolevulinicacid-mediated photodynamic therapy on MCF-7 cells
Journal: Photodiagnosis and Photodynamic Therapy
Authors: K Hotowy, M Woźniak, K Duś, E Czapińska, B Osiecka, ...
Citation: 8
Title: Large-scale proteomic analysis of follicular lymphoma reveals extensive remodeling of cell adhesion pathway and identifies hub proteins related to the lymphomagenesis
Journal: Cancers
Authors: K Duś-Szachniewicz, G Rymkiewicz, AK Agrawal, P Kołodziej, ...
Citation: 7
Conclusion
Assoc. Prof. Dr. Kamila Dus-Szachniewicz represents a leading figure in modern translational oncology, driven by her expertise in Experimental Methods. Her educational background, professional achievements, research leadership, and impactful publications converge to form a profile that illustrates the transformative power of Experimental Methods in advancing medical science. Through proteomics, tumor modeling, and optical manipulation technologies, she has demonstrated how Experimental Methods can bridge the gap between fundamental biology and clinical applications. This conclusion underscores her vital role in shaping future diagnostic and therapeutic strategies, inspiring continued development of Experimental Methods that will refine and personalize cancer care for improved patient outcomes.