Dr. Dipesh Khanal | Experimental Methods | Best Researcher Award
Dr. Dipesh Khanal, The University of Sydney, Australia
Dr. Dipesh Khanal is a Postdoctoral Fellow and Nano-characterisation theme leader at the University of Sydney’s Pharmacy School. He earned his Ph.D. in Pharmaceutics from the same institution in 2018 and holds a Master of Pharmacy from Kathmandu University, Nepal, where he graduated Magna Cum Laude. Dr. Khanal specializes in nano-characterisation, pulmonary formulations, and advanced drug delivery systems. His research is funded by prestigious bodies like the US FDA, and he has been recognized with awards for his contributions to nanoscale toxicology and aerosol drug delivery.
Educational Details
Dr. Dipesh Khanal is a Postdoctoral Fellow and Nano-characterisation theme leader at the Advanced Drug Delivery Group, Sydney Pharmacy School, The University of Sydney. He holds a Ph.D. in Pharmaceutics from The University of Sydney (2014-2018) and a Master of Pharmacy (Magna Cum Laude) from Kathmandu University, Nepal (2009-2011), where he was the batch topper. He earned his Bachelor of Pharmacy from the same institution in 2006.
Professional Experience
Dr. Khanal has been a postdoctoral fellow since 2018, where he has played a pivotal role in advancing nano-characterisation and biopharmaceutical formulations. His expertise includes particle production techniques like spray drying, lyophilization, and air jet milling. He has developed advanced analytical techniques such as AFM-IR spectroscopy and optical photothermal infrared spectroscopy for nanoparticle characterization. Dr. Khanal has successfully secured competitive funding, including grants from the US FDA, ARC, and NSW funding bodies. He has co-supervised two PhD students and managed high-impact research projects, particularly in pulmonary formulations, aerosol characterization, and bacteriophage tablet formulation.
Research Interest
Dr. Khanal specializes in nano-characterisation, nanotechnology in drug delivery, pulmonary formulations, and the mechanical analysis of nanoparticles. His research explores aerosol delivery systems, nanotoxicity assessment, and the development of analytical methods to characterize drug nanocrystals within liposomes.
Grants and Awards
2023 Provost’s CAPEX Fund: AUD 756,000 for a Multimodal, Correlative, and Multiscale Characterisation Platform.
2022 US FDA Research Support: USD 1.25 million for nanospectroscopy and nano-thermal analysis of drug aerosols.
2019 Sydney Nano Publication Award: For a paper on nanodiamond particles and nanotoxicity assessment.
2018 Nanoscale Horizons Outstanding Paper Award: For nanoscale characterization using AFM-IR spectroscopy.
2017 Award for reducing the use of animals in research via 3D scaffold-free liver models for nanotoxicity studies.
Top Notable Publications
Khanal, D., Cao, Y., Tai, W., & Kim Chan, H. (2024). O-PTIR spectroscopy for characterizing active pharmaceutical ingredient specific particle size distributions of nasal spray suspension products. International Journal of Pharmaceutics, 664, 124653.
Zhang, J., Khanal, D., Chan, H.-K., & Banaszak Holl, M.M. (2024). Nanoscale colocalized thermal and chemical mapping of pharmaceutical powder aerosols. International Journal of Pharmaceutics, 656, 124116.
Cao, Y., Khanal, D., Kim, J., Banaszak Holl, M.M., & Chan, H.-K. (2023). Stability of bacteriophages in organic solvents for formulations. International Journal of Pharmaceutics, 646, 123505.
Wang, Y., Khanal, D., Alreja, A.B., Britton, W.J., & Chan, H.-K. (2023). Bacteriophage endolysin powders for inhaled delivery against pulmonary infections. International Journal of Pharmaceutics, 635, 122679.
Khanal, D., Kim, J., Zhang, J., Holl, M.M.B., & Chan, H.-K. (2023). Optical photothermal infrared spectroscopy for nanochemical analysis of pharmaceutical dry powder aerosols. International Journal of Pharmaceutics, 632, 122563.
Zhang, J., Khanal, D., & Banaszak Holl, M.M. (2023). Applications of AFM-IR for drug delivery vector characterization: infrared, thermal, and mechanical characterization at the nanoscale. Advanced Drug Delivery Reviews, 192, 114646.
Albariqi, A.H., Ke, W.-R., Khanal, D., Drago, J., & Chan, H.-K. (2022). Preparation and characterization of inhalable ivermectin powders as a potential COVID-19 therapy. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 35(5), 239–251.
Global Collaboration and Leadership
He has established successful collaborations with regulatory authorities like the US FDA, academic partners globally, and industries. His role in leading research teams, managing significant projects, and fostering collaborations reflects his leadership and organizational capabilities, which are critical attributes for this award.
Conclusion
Dr. Dipesh Khanal’s profound contributions to nanotechnology, drug delivery systems, and his leadership in pharmaceutical research make him an excellent contender for the Research for Best Researcher Award. His work not only demonstrates scientific innovation but also holds real-world applicability in medicine, regulatory science, and industrial research. His accomplishments align well with the award’s emphasis on research innovation, publication record, and community impact.